Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
2006
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: - Guidance on information requirements and chemical safety assessment (Chapter R.11.1.4.1: Assessment of substances requiring special considerations with regard to testing) - Valid method similar to Annex V, A.8, 1.6.1, 67/548/EEC
Cross-reference
Reason / purpose:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report Date:
2005

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Measuring the solubility in water and in n-octanol (see below for details) seperately. Calculation of octanol-water partition coefficient from single values.
Type of method:
other: see below
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
other: chromatography and UV-vis spectrometry

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
ca. 2.5
Temp.:
24 °C
pH:
ca. 7

Any other information on results incl. tables

Solubility in water: 9.80 µg/L (sigma = 1.68) at 24 - 25°C

Solubility in octanol: 3.31 mg/L (sigma = 0.15) at 24 - 25°C

Applicant's summary and conclusion

Executive summary:

The calculated log Pow of Pigment Red 112 is 2.5.