3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide

Nanomaterial dustiness

Administrative data

Endpoint:

nanomaterial dustiness

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods

Remarks:

according to DIN EN 17199-3

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Report date:

2020

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: DIN EN 17199-3

Version / remarks:

measurement of dustiness of bulk materials that contain or release respirable NOAA or other respirable particles - Part 3: Continuous drop method

Deviations:

yes

Remarks:

test conditions (temperature, humidity) due to laboratory environment; 1 meaurement performed

GLP compliance:

no

Type of method:

continuous drop

Sampling:

The test material was used without further treatment (e.g. drying). 77.6 g (443.4 cm3) test material are used for the measurement, dosing rate: 7.8 g/min

Test material

Test material information

Constituent 1

Reference substance name:

3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide

EC Number:

229-440-3

EC Name:

3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide

Cas Number:

6535-46-2

Molecular formula:

C24H16Cl3N3O2

IUPAC Name:

3-hydroxy-N-(2-methylphenyl)-4-[(2,4,5-trichlorophenyl)diazenyl]-2-naphthamide

Test material form:

solid: nanoform, no surface treatment

Results and discussion

Dustiness index

Dustiness index 1

Key result

Mean:

314 652.81 other: 1/mg

Remarks on result:

other: dustiness index as number of airborne particles per mg in the nanoscale (10 nm - 100 nm)

Dustiness index 2

Mean:

46 069.92 other: N/cm3

Remarks on result:

other: number of airborne nanoparticles per cm3

Any other information on results incl. tables

measurement duration: 10 min

temperature: 21°C, rel. air humidity 45 %

The cleaned, almost particle-free air had a total particle count of 6 particles/cm³ in the range of 10 nm - 417 nm, the nanoscale fraction (10 - 100 nm) contained 4 particles/cm³.

table 1: summary SMPS (sanning mobility particle sizer)

Range [nm]	Mean [nm]	Concentration [N/cm^3]	ICD[1/mg]	ECD[1/mg x s]
10 - 100	72.57	46069.92	314652.81	524.42
100 - 417	153.49	92577.94	632297.80	1053.83
10 - 417	126.60	138647.86	946950.61	1578.25

I_CD: dustiness index as number of airborne particles per mg

E_CD: emission rate as number of particles per mg per second

mean: average particle diameter in nm

N: number of airborne particles

table 2: summary OPS (optical particle sizer)

Range [µm]	Mean [µm]	Concentration [N/cm^3]	ICD[1/mg]	ECD[1/mg x s]
0.3 - 10	5.48	360.70	2463.53	4.11

Applicant's summary and conclusion

Executive summary:

The dusting behaviour of the test material was investigated using DIN EN 17199 -3: 2019 -12 "workplace exposure - measurement of dustiness of bulk materials that contain or release respirable nano objects and their aggregates and agglomerates or other respirable particles- Part 3: Copntinuous drop method".

The dust released by the falling test material was measured by a scanning mobility particle sizer (SMPS, 10 - 417 nm) and an optical particle sizer (3 - 10 µm). The counterflow was provided by cleaned, almost particle-free air.

The SMPS counted 138647.86 particles per cm³ (in the nanoscale (10 - 100 m) 46069.92 particles per cm³) corresponding to a dustiness index of 946950.61 particles per mg (in the nanoscale (10 - 100 nm) 314652.81 particles per mg). The mean size of the nanoparticles was 126.60 nm, the mean size of particles in the range 10 - 417 nm was 72.57.

The OPS (0.3 - 10 µm) counted 360.70 particles per cm³ corresponding to a dustiness index of 2463.53 particles per mg. The mean size of the particles was 5.48 µm.