Registration Dossier
Registration Dossier
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EC number: 240-896-2 | CAS number: 16871-90-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Disodium hexafluorosilicate
Results on skin irritation obtained from literature indicate that damage caused on intact skin after application of 4h of tdisodium hexafluorosilicate under occlusion provide reversible irritating effects. If applied for 23h, reversibility is also observed. Reversibility of the lesions was complete by day 7. Irritating effects were measured based on PCI values. For disodium hexafluorosilicate, PCI= 0.04, which corresponds to non irritating. The value of the pH given by the substance seemed not to have any effects on PCI.
Experimental in vitro eye irritation study demonstrated that disodium hexafluorosilicate is not eye irritating.
Experimental results and available and reliable studies published show that disodium hexafluorosilicate is not irritant on in vitro studies.
Dipotassium hexafluorosilicate
As irritating properties should not be attributed to the presence of sodium or potassium ions, dipotassium hexafluorosilicate is not expected to be irritant.Justification for classification or non-classification
No classification is proposed since experimental results and data on reliable publications indicate the absence of irritating properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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