Registration Dossier
Registration Dossier
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EC number: 202-429-0 | CAS number: 95-53-4
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- other: review
- Adequacy of study:
- supporting study
- Reliability:
- other: peer-reviewed publication
- Rationale for reliability incl. deficiencies:
- other: peer reviewed publication
Data source
Reference
- Reference Type:
- publication
- Title:
- o-TOLUIDINE CAS No: 95-53-4 SIDS Initial Assessment Report.
- Author:
- CICAD 1998 cited in OECD SIDS
- Year:
- 2 006
- Bibliographic source:
- UNEP Publications
Materials and methods
- Type of study / information:
- citation of a review
- Endpoint addressed:
- basic toxicokinetics
Test material
- Reference substance name:
- o-toluidine
- EC Number:
- 202-429-0
- EC Name:
- o-toluidine
- Cas Number:
- 95-53-4
- Molecular formula:
- C7H9N
- IUPAC Name:
- 2-methylaniline
- Test material form:
- other: liquid
Constituent 1
Results and discussion
- Results:
- Biological monitoring to assess human exposure to o-toluidine indicates that absorption may occur through inhalation and dermal contact;
however,quantitative information was not identified. o-toluidine bindes to hemoglobin. N-acetylated metabolites of o-toluidine are eliminated
in the urine.
Applicant's summary and conclusion
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