Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only result reported; no information on method and test performance

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1979
Report date:
1979

Materials and methods

Principles of method if other than guideline:
Method: other: Fermentation tube test; toxicity measured as inhibition of anaerobic production of methane; no guideline stated
GLP compliance:
no
Remarks:
pre-GLP study

Test material

Constituent 1
Chemical structure
Reference substance name:
Valeric acid
EC Number:
203-677-2
EC Name:
Valeric acid
Cas Number:
109-52-4
Molecular formula:
C5H10O2
IUPAC Name:
pentanoic acid
Details on test material:
- Name of test material (as cited in study report): n-Valeriansäure
- no further data

Test organisms

Test organisms (species):
other: no data

Results and discussion

Effect concentrations
Dose descriptor:
NOEC
Effect conc.:
1 500 mg/L
Remarks on result:
other: Toxic Threshold Concentration (TGK) was initially reported, i.e. concentration without adverse effects

Applicant's summary and conclusion

Validity criteria fulfilled:
no
Conclusions:
Toxicity of valeric acid to microorganisms was low.
Executive summary:

Toxicity of valeric acid to microorganisms was low, as reportedly there was no toxicity at 1500 mg/L in the fermentation tube test. Reliability of this resulkt is low due to missing documentation (Hoechst AG, 1979).