Valeric acid

Toxicity to microorganisms

Administrative data

Endpoint:

toxicity to microorganisms

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Only result reported; no information on method and test performance

Data source

Reference

Reference Type:

other company data

Title:

Unnamed

Year:

1979

Report date:

1979

Materials and methods

Principles of method if other than guideline:

Method: other: Fermentation tube test; toxicity measured as inhibition of anaerobic production of methane; no guideline stated

GLP compliance:

no

Remarks:

pre-GLP study

Test material

Test material information

Constituent 1

Reference substance name:

Valeric acid

EC Number:

203-677-2

EC Name:

Valeric acid

Cas Number:

109-52-4

Molecular formula:

C5H10O2

IUPAC Name:

pentanoic acid

Details on test material:

- Name of test material (as cited in study report): n-Valeriansäure
- no further data

Test organisms

Test organisms (species):

other: no data

Results and discussion

Effect concentrations

Dose descriptor:

NOEC

Effect conc.:

1 500 mg/L

Remarks on result:

other: Toxic Threshold Concentration (TGK) was initially reported, i.e. concentration without adverse effects

Applicant's summary and conclusion

Validity criteria fulfilled:

no

Conclusions:

Toxicity of valeric acid to microorganisms was low.

Executive summary:

Toxicity of valeric acid to microorganisms was low, as reportedly there was no toxicity at 1500 mg/L in the fermentation tube test. Reliability of this resulkt is low due to missing documentation (Hoechst AG, 1979).