Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-677-2 | CAS number: 109-52-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Two GLP-studies according to OECD guideline 201 - one study conducted with pure valeric acid and one study conducted with a mixture of valeric
acid and 2-methylbutyric acid - are available.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 29.3 mg/L
Additional information
Two studies are available to assess the acute toxicity of valeric acid to algae. A GLP-guideline study conducted with pure valeric acid
has been selected as the key study as this study is reliable without restrictions (Klimisch 1). The ErC50 (72 hours) reported in this study is 29.3 mg/l. This enpoint is supported by a GLP-study conducted with a commercial mixture of valeric acid (ca. 64%) and 2 -methylbutyric acid (ca. 36%). The ErC50 (48 hours) reported in this supporting study is 73.2 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
