Registration Dossier
Registration Dossier
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EC number: 203-677-2 | CAS number: 109-52-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
A non-GLP study similar to OECD guideline 203 is available for valeric acid and a GLP-study according to OECD guideline 203 is available for a
mixture of valeric acid and 2-methylbutyric acid. A third study with limited documentation is also provided.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 39 mg/L
Additional information
Three studies are available to assess the acute toxicity of valeric acid to fish. A non-GLP study conducted with pure valeric acid
and Pimephales promelas has been selected as the key study. The LC50 (96 hours) reported in this study is 39 mg/l. These data are supported by a GLP study conducted with a commercial mixture of valeric acid (ca. 64%) and 2 -methylbutyric acid (ca. 36%) and Rainbow Trout. The LC50 (96 hours) reported in this supporting study is 75.9 mg/l. A third, non-GLP study has also been included which was assigned a Klimisch score of 3 due to limited documentation. This study reported a short-term NOEC of 500 mg/L for the golden orfe exposed to pure valeric acid.
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