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EC number: 231-135-5
CAS number: 7440-25-7
1 Effects of Implanted Tantalum on Maternal Parameters
12 Implanted Ta Pellets
# Dams bred
Days to pregnancy (SEM)
3.9 (± 1.76)
2.08 (± 0.23)
Mean weight gain (g)
133.79 (± 8.13)
138.32 (± 6.49)
Mean food intake (g)
23.44 (± 0.67)
24.51 (± 0.68)
Mean water intake (mL)
43.85 (± 2.59)
44.45 (± 2.60)
2 Effects of Tantalum on Litter Data
Total # foetuses
13.8 (± 0.79)
13..5 (± 0.78)
Average pup weight
3.56 (± 0.20)
3.164 (± 0.09)
A study was conducted to investigate the transfer of depleted uranium
from mother to foetus to gain an understanding of the degree of foetal
exposure from maternally implanted uranium. The impact of the depleted
uranium on the dam’s ability to become pregnant and carry her litter to
term was also investigated. Tantalum was used in the study as a
chemically inert control.
Pregnant rats were monitored daily for weight gain, food intake and
water intake. Following euthanisation, dams were immediately subjected
to caesarean-section. The uterine horns were removed and foetuses were
Litters were examined and a record made of the total number of foetuses,
the number of viable foetuses, the sex ratio and any overt signs of
No effects were seen on the litters relating to the number of pups, the
number of males vs. females and foetal weights. All litters were
examined for overt signs of teratology and none were noted.
There were no effects reported in this study relating to maternal
implantation of the test material.
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