Registration Dossier
Registration Dossier
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EC number: 500-012-0 | CAS number: 9004-77-7
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- sub-chronic toxicity: oral
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Justification for type of information:
- For justification of read across see category justification attached to category object.
Data source
Materials and methods
Test material
- Reference substance name:
- Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy-
- EC Number:
- 500-012-0
- EC Name:
- Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy-
- Cas Number:
- 9004-77-7
- Molecular formula:
- (C2H4O)nC4H10O
- IUPAC Name:
- 2-butoxyethan-1-ol
1
Results and discussion
Effect levels
- Dose descriptor:
- NOAEL
- Effect level:
- 500 mg/kg bw/day (nominal)
- Based on:
- test mat.
- Sex:
- male/female
- Remarks on result:
- other: based on a weighted average consideration of the results for this substance based on other substances within the category. Results corrected for molecular weight differences.
- Remarks:
- A sub-acute bridging study is being carried out on this substance to add confidence to bridging between members of this category.
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
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Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
