Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26-04-2010 to 01-07-2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The GLP study was performed according to OECD Test Guideline 117, with no reported or observed deviations.
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes
Remarks:
OECD GLP
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Type:
Pow
Partition coefficient:
415
Temp.:
30 °C
Remarks on result:
other: The pH of the test solution was not reported but the pH of the buffer solution used was 6.09
Type:
log Pow
Partition coefficient:
2.62
Temp.:
30 °C
Remarks on result:
other: The pH of the test solution was not reported but the pH of the buffer solution used was 6.09
Conclusions:
The logarithm of the partition coefficient (log Kow) for Anisole was determined to be 2.62 at 30 degrees C.

Description of key information

Several peer-reviewed sources indicate the logarithm of the octanol-water partition coefficient of Anisole is 2.11.  A K1 study conducted on 97.06% pure anisole showed a log Kow of 2.62.

Key value for chemical safety assessment

Log Kow (Log Pow):
2.62

Additional information