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Ecotoxicological information

Toxicity to other aquatic organisms

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Description of key information

Many high quality studies are available in the database of toxicity to other aquatic vertebrates. A lumped data set for nickel-based compounds was considered for endpoint coverage. 


The lowest EC50 is 0.146 mg Ni/L for Xenopus laevis (Hopfer et al., 1991) and the highest EC50 is 3.740 mg Ni/L for Bufo terrestris (Fort et al., 2006). The LC50 values range from 0.420 mg Ni/L for Ambystoma opacum (Birge et al., 1978) to 21.42 mg Ni/L for Ambystoma opacum (Hopfer et al, 1991).

Additional information

Toxicity to Amphibians:


NOEC/L(E)C10 data are available for three species of amphibians, with values ranging from 84.5 µg Ni/L to 13.147 µg Ni/L, both values from Xenopus laevis (Hopfer et al., 1991).


The following table indicates those NOEC or EC10 values of high quality that have been carried forward for the HC5 & PNEC derivation.


 











































  Key Study


(freshwater amphibians)



Selected values for the most sensitive endpoints used for derivation of the freshwater HC5


 

Species



Endpoint



Value (ug/L) Ni


 

Hopfer et al., 1991



Xenopus laevis



EC10



84.5


 

Fort et al., 2004



Xenopus laevis



EC10



230-260


 

Bufo terrestris



NOEC



640


 

Gastrophryne carolensis



LC10



180-190