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EC number: 233-071-3 | CAS number: 10028-18-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to other aquatic organisms
Administrative data
Link to relevant study record(s)
Description of key information
Many high quality studies are available in the database of toxicity to other aquatic vertebrates. A lumped data set for nickel-based compounds was considered for endpoint coverage.
The lowest EC50 is 0.146 mg Ni/L for Xenopus laevis (Hopfer et al., 1991) and the highest EC50 is 3.740 mg Ni/L for Bufo terrestris (Fort et al., 2006). The LC50 values range from 0.420 mg Ni/L for Ambystoma opacum (Birge et al., 1978) to 21.42 mg Ni/L for Ambystoma opacum (Hopfer et al, 1991).
Additional information
Toxicity to Amphibians:
NOEC/L(E)C10 data are available for three species of amphibians, with values ranging from 84.5 µg Ni/L to 13.147 µg Ni/L, both values from Xenopus laevis (Hopfer et al., 1991).
The following table indicates those NOEC or EC10 values of high quality that have been carried forward for the HC5 & PNEC derivation.
Key Study (freshwater amphibians) | Selected values for the most sensitive endpoints used for derivation of the freshwater HC5 | |||
Species | Endpoint | Value (ug/L) Ni | ||
Hopfer et al., 1991 | Xenopus laevis | EC10 | 84.5 | |
Fort et al., 2004 | Xenopus laevis | EC10 | 230-260 | |
Bufo terrestris | NOEC | 640 | ||
Gastrophryne carolensis | LC10 | 180-190 | ||
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