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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: No detail included in methodology and results. All studies included in the report are brief summaries.
Justification for type of information:
Supporting data only.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1971
Report date:
1971

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No details on methodology included within study report.
GLP compliance:
not specified
Test type:
other: No data

Test material

Constituent 1
Chemical structure
Reference substance name:
Pentapotassium triphosphate
EC Number:
237-574-9
EC Name:
Pentapotassium triphosphate
Cas Number:
13845-36-8
Molecular formula:
H5O10P3.5K
IUPAC Name:
pentapotassium triphosphate
Details on test material:
- Name of test material : potassium tripolyphosphate
- Analytical purity: No data

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
No data

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Details on dermal exposure:
No data
Duration of exposure:
No data
Doses:
4640 mg/kg
No. of animals per sex per dose:
2 animals per dose
Control animals:
not specified
Details on study design:
- Duration of observation period following administration: 14 days
- Necropsy of survivors performed: yes
- Other examinations performed: clinical signs
Statistics:
No data

Results and discussion

Preliminary study:
Not applicable
Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 4 640 mg/kg bw
Mortality:
No unscheduled deaths were recorded during the study
Clinical signs:
other: No signs of toxicity were noted. Moderate erythema and oedema were noted.
Gross pathology:
No data (not examined)
Other findings:
No data

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Not specified Criteria used for interpretation of results: EU
Conclusions:
The acute dermal LD50 for potassium tripolyphosphate in rabbits was determined to be > 4640 mg/kg.