Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1981
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only short report, method / subjects not described. Only english summary, report written in french.

Data source

Reference
Reference Type:
publication
Title:
Irritation et Allergie aux Acrylates et Méthacrylates - Première partie - Monoacrylates et Monométhacrylates Simples
Author:
Cavalier, C., Jelen, G., Hervé-Bazin, B., Foussereau, J.
Year:
1981
Bibliographic source:
Ann. Dermatol. Venereol. (Paris) .: 108, 549 - 556

Materials and methods

Study type:
study with volunteers
Endpoint addressed:
skin irritation / corrosion
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Allyl methacrylate was tested for skin irritation in concentrations of 3 and 10% in olive oil.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Allyl methacrylate
EC Number:
202-473-0
EC Name:
Allyl methacrylate
Cas Number:
96-05-9
Molecular formula:
C7H10O2
IUPAC Name:
allyl methacrylate
Test material form:
other: liquid

Method

Type of population:
not specified
Subjects:
no data
Ethical approval:
not specified
Route of exposure:
dermal
Reason of exposure:
other: no data
Exposure assessment:
measured

Results and discussion

Clinical signs:
3% allyl methacrylate caused skin irritation (without pustules) at 3 of 11 persons (no results were reported for the 10% solution)

Applicant's summary and conclusion