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Boiling point

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Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2007
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry
Boiling pt.:
226 K
Atm. press.:
102.14 kPa

Determination 1:

Boiling point 225.26°C (498 K) at 102.14 kPa

Determination 2:

Boiling point 226.11°C (499 K) at 102.14 kPa

Mean boiling temperature: 499 ± 0.5 K at 102.14 kPa

Conclusions:
The boiling point of the test substance was measured to be 499 ± 0.5 K at 102.14 kPa (226°C), determined in a reliable study according to an appropriate test protocol and in compliance with GLP. The result is considered reliable.
Endpoint:
boiling point
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR prediction
Principles of method if other than guideline:
The result was obtained using an appropriate QSAR method (See attached QMRF and QPRF for details)
Boiling pt.:
482 K
Atm. press.:
1 013 hPa
Boiling pt.:
209 °C
Atm. press.:
1 013 hPa
Conclusions:
A boiling point value of 209°C has been obtained for the test substance using an appropriate estimation method. The result is considered reliable.

Description of key information

Boiling point (trimethoxyphenylsilane): 226°C at 102.14 kPa (OECD guideline 103)

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
226 °C

Additional information

A boiling point value of 226°C at 102.14 kPa was reported based on a standard guideline study (OECD Guideline 103 Boiling point/boiling range). The result is considered to be reliable and was selected as the key study. A value of 211°C was available in a handbook, to which reliability could not be assigned. A predicted value of 209°C, calculated using a validated predictive method, is also available.