Registration Dossier
Registration Dossier
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EC number: 293-054-1 | CAS number: 91051-05-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects on microorganisms were observed at the highest test concentration
Key value for chemical safety assessment
Additional information
There are no studies available on the toxicity of Fatty acids essential, Et esters (CAS 91051 -05 -7) to microorganisms. The assessment was therefore based on a study conducted with the structurally most similar category member, for which data is available, Ethyl linoleate (CAS 544-35-4), as part of a read across approach, which is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Further justification is given within the endpoint summary 6.1 and within the category justification section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was entered into IUCLID. Nevertheless, as can be seen in the data matrix of the category justification in Section 13, all reliable data in the category support the hazard assessment for this endpoint, by showing a consistent pattern of results.
In the read-across study, the acute toxicity to activated sludge was tested with Ethyl linoleate according to OECD 209 and to GLP (Desmares-Koopmans 2010). After an incubation time of 3 hours, there was no inhibition of the respiration rate observed at the tested concentration of 100 mg/L, resulting in an EC50(3h) value of >100 mg/L.
Thus, based on the above mentioned result, and due to the structural and profile similarities of the substances, as are explained with in the overall endpoint summary 6.1 it can be concluded that no toxicological effects on microorganisms are expected for Fatty acids, essential, Et esters (CAS 91051-05-7).
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