Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

SKIN IRRITATION:
2 studies including key study with conclusion; not irritating
EYE IRRITATION
2 studies, both concluding not irritating.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Two studies are available that examined the skin irritancy potential of 2 -(2 -methoxyethoxy)ethanol using the guideline exposure time (4 hours). Both show neglibile to minimal irritancy. The key study is selected as the one showing the 'worst' results.

There is more limited data available on the eye irritancy potential, however, a study similar to guideline is reported in sufficient detail to be able to ascertain that the substance also has very low eye irritancy potential, with effects disappearing within 24 hours of instillation of the substance into rabbit eyes.

Justification for classification or non-classification

This substance is not irritating to the skin following single application and does not meet the criteria for classification as a skin irritant.

There is limited but sufficient data available on the eye irritancy potential to make an unequivocal comparison with classification criteria and to conclude that the substance does not meet the criteria to be classified as irritating to the eye.