Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

Dermal sensitisation has been investigated in a maximisation test according to OECD test methods. A marked sensitisation response was observed to tetrahydrophthalic anhydride following a period of induction exposure


Migrated from Short description of key information:
Skin sensitisation: sensitising

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

Allergic reactions of the skin and allergic respiratory reactions are known effects of occupational exposure to cyclic acid anhydrides (Concise International Chemical Assessment Document 75 - Cyclic Acid Anhydrides: Human Health Aspects,World Health Organization, 2009).


Migrated from Short description of key information:
Respiratory sensitisation: sensitising

Justification for classification or non-classification

Allergic reactions of the skin and allergic respiratory reactions are known effects of occupational exposure to cyclic acid anhydrides (Concise International Chemical Assessment Document 75 - Cyclic Acid Anhydrides: Human Health Aspects,World Health Organization, 2009). This is reflected in current classification and labelling of the substance.