Antimony nickel titanium rutile

Specific investigations: other studies

Administrative data

Endpoint:

specific investigations: other studies

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2006

Report date:

2006

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: DIN EN 1811

GLP compliance:

yes

Type of method:

other: abiotic

Test material

Test material information

Constituent 1

Reference substance name:

Antimony nickel titanium rutile

EC Number:

701-459-6

Cas Number:

8007-18-9

Molecular formula:

Ni(x/3)Sb(2x/3)Ti(1-x)O2 0,1≤x≤0,3

IUPAC Name:

Antimony nickel titanium rutile

Test material form:

solid

Specific details on test material used for the study:

- Batch No. 32954-109-5
- Storage conditions: room temperature

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: Ni-Sb-Ti-oxid treated with acid

Test animals

Species:

other: abiotic test

Administration / exposure

Details on study design:

Determination of Ni, Sb and Ti after elution of the test item in artificial sweat at pH 6.5 (1.0008 g urea, 5.0021 g NaCl and 940 µL lactic acid were dissolved in 900 mL deionised water enriched with O2; pH adjustment with 1% ammonium hydroxide solution) and at pH 8.5 and 1.0 was performed as followed: About 3 mg of the test item was added to 100 mL elution medium. The vessels were covered and heated (without stirring) during one week at 30°C. The pH was measured in each vessel (after 1,2,3, 6 and 7 days) and adjusted to pH if necessary. After 7 days two samples were drawn from each vessel and passed through a 0.22 pm syringe filter, then acidified with HNO3, and analysed for total dissolved metal concentration by inductively coupled plasma - mass spectrometry (ICP-MS).

Results and discussion

Any other information on results incl. tables

Release of metals (d)

Sample name	d(Ni)	d(Sb)	d(Ti)
	µg/cm2/Week	µg/cm2/Week	µg/cm2/Week
artificial sweat #1	<0,0001	<0,0001	0,0001
artificial sweat #2	<0,0001	<0,0001	0,0001
Mean artificial sweat	<0,0001	<0,0001	0,0001
pH 8,5 #1	<0,0001	<0,0001	<0,0001
pH 8,5 #2	<0,0001	<0,0001	<0,0001
Mean pH 8.5	<0,0001	<0,0001	<0,0001
pH 1.0 #1	<0,0001	<0,0001	0,0007
pH 1.0 #2	0,0001	<0,0001	0,0007
Mean pH 1.0	0,0001	<0,0001	0,0007