Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to terrestrial plants

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

No terrestrial plant toxicity studies are available for pentasodium DTPA.  Terrestrial toxicity testing is deemed not necessary for Pentasodium DTPA since there is no direct application to soils.

Key value for chemical safety assessment

Additional information

Soil exposure is unlikely, since there is no direct application of Pentasodium DTPA on soils. Furthermore, Pentasodium DTPA is not expected to adsorb to soils based upon the known behaviour of EDTA, a structural analogue. In a laboratory test, solutions of H4EDTA and ZnEDTA were eluted through various surface soils and were found to move quite readily through the soils and be only very slightly adsorbed (Cheng et al., 1972). A model calculation of the distribution of EDTA metal complexes between water and suspended solids resulted in a finding that <1% of the total EDTA is adsorbed, and according to the fugacity model Mackay level I, the preferred environmental component for EDTA is the hydrosphere (99.999%) (EU, 2004).  Read-across from EDTA to DTPA is supported by the fact that the EDTA and DTPA have similar chemical structures and the same mechanism of action (chelation of metals).Thus, based on a read across approach from EDTA, low adsorption is predicted for DTPA, and soil testing is therefore further demonstrated to be not necessary for DTPA, especially since there is not direct application of Pentasodium DTPA to soils.

Cheng SM, Thomas RL, Elrick DE. 1972. Reactions and movements of EDTA and ZNEDTA in soils. Can. J. Soil. Sci. 52:337 -341.

European Union (EU). 2004. European Union Risk Assessment Report: edetic acid (EDTA)