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Based on the read-across substance, methyl ethyl ketone (CAS No. 78-93-3), the substance is predicted to possess a 96-hour LC50 in freshwater fish of 2993 mg/L, a 48-hour EC50 in daphnia magna of 308 mg/L and a 96-hour EC50 in aquatic algae and cyanobacteria of 2029 mg/L. The toxicity threshold, which is approximately equivalent to the LC3, for microorganism was determined to be 500 mg/L. This substance is not considered to be acutely toxic to fish, or aquatic invertebrates, nor is it considered to be toxic to aquatic algae, cyanobacteria, or microorganisms.