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Toxicity to soil microorganisms

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Description of key information

EC50 > 1000 mg/kg dw soil

Key value for chemical safety assessment

Additional information

Since no experimental data investigating the effects on soil microorganisms are available for fatty acids, C16-18 and C18-unsatd., tetraesters with pentaerythritol (CAS 68604-44-4), in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read across to a structurally related group member 2,2-bis(hydroxymethyl)-1,3-propanediyl dioleate (CAS 25151-96-6) was conducted. This read-across is justified in detail in the overall summary (IUCLID chapter 6.1) and within the category justification in IUCLID Section 13. Both substances are esters with pentaerythritol as alcohol and exhibit longer carbon chain lengths (≥ C16).

In the GLP study the toxicity to soil micro-organisms with 2,2-bis(hydroxymethyl)-1,3-propanediyl dioleate (CAS 25151-96-6) was tested according to OECD 216. The EC50 for the nitrogen transformation was calculated to be > 1000 mg/kg dw soil (the highest concentration tested). This result concludes that there were no long term adverse effects on nitrogen transformation in soils.

Based on the results from a structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by an equal ecotoxicological profile, it can be concluded that fatty acids, C16-18 and C18-unsatd., tetraesters with pentaerythritol (CAS 68604-44-4) will not exhibit effects on soil microflora.

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