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EC number: 271-756-9 | CAS number: 68607-24-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1990-08-2 to 1990-09-03
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: According OECD 209, non GLP, limited information on test substance
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Deviations:
- yes
- Remarks:
- Instead of using 3,5-dichlorophenol as reference (acc. to OECD 209) potassium dichromate was used in a concentration to inhibit respiration of 50%.
- Principles of method if other than guideline:
- Instead of using 3,5-dichlorophenol as reference (acc. to OECD 209) potassium dichromate was used in a concentration to inhibit respiration of 50%.
- GLP compliance:
- no
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
no furhter details are available - Analytical monitoring:
- no
- Details on sampling:
- not applicable as nominal test concentrations are evaluated
- Vehicle:
- no
- Details on test solutions:
- no further details available
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- - Laboratory culture: activated sludge from municipal waste water treatment plant Hildesheim
- Method of cultivation:
- Preparation of inoculum for exposure: washed twice with dechlorinated, autoclaved tap water
- Pretreatment: none
- Initial biomass concentration: 1.251 g/L dry weight - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
- Post exposure observation period:
- not applicable
- Hardness:
- not specified
- Test temperature:
- 22°C
- pH:
- not specified
- Dissolved oxygen:
- not specified
- Salinity:
- not specified
- Nominal and measured concentrations:
- nominal: 10 - 18 - 32 - 58 - 100 - 180 mg/L
- Details on test conditions:
- TEST SYSTEM
TEST SYSTEM
- Test vessel:500 mL Erlenmeyer flasks
- Type (delete if not applicable): not specified
- Material, size, headspace, fill volume: 500mL
- Aeration: yes, permanently
- Type of flow-through (e.g. peristaltic or proportional diluter): not specified
- Renewal rate of test solution (frequency/flow rate):not specified
- No. of organisms per vessel:not specified
- No. of vessels per concentration (replicates):1
- No. of vessels per control (replicates):1
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: synthetic water acc. to OECD 209
OTHER TEST CONDITIONS
- Adjustment of pH: not specified
- Photoperiod: not specified
- Light intensity: not specified
- Reference substance (positive control):
- yes
- Remarks:
- kaliumdichromat
- Key result
- Duration:
- 3 h
- Dose descriptor:
- EC10
- Effect conc.:
- 9.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Remarks on result:
- other: n.a.
- Duration:
- 3 h
- Dose descriptor:
- other: EC20
- Effect conc.:
- 16 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Remarks on result:
- other: n.a.
- Key result
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- 43 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Remarks on result:
- other: n.a.
- Duration:
- 3 h
- Dose descriptor:
- other: EC80
- Effect conc.:
- 120 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Remarks on result:
- other: n.a.
- Details on results:
- no further details available
- Results with reference substance (positive control):
- - Results with reference substance valid? yes
- Relevant effect levels: 32 - 58 - 100 mg/ L - Reported statistics and error estimates:
- no further details available
- Validity criteria fulfilled:
- yes
- Conclusions:
- Test results are plausible and valid:
EC 10-Wert: 9.5 mg/L
EC 20-Wert: 16 mg/L
EC 50-Wert: 43 mg/L
EC 80-Wert: 120 mg/L
P 95 %: 11.26 < 43 < 164.17 - Executive summary:
Test results are plausible and valid. Level of detail in the report reflect testing strategy and reporting of 1990.
Reference
no further details available
Description of key information
Test results are plausible and valid:
EC 10-Wert: 9.5 mg/L
EC 20-Wert: 16 mg/L
EC 50-Wert: 43 mg/L
EC 80-Wert: 120 mg/L
P 95 %: 11.26 < 43 < 164.17
Key value for chemical safety assessment
- EC50 for microorganisms:
- 43 mg/L
- EC10 or NOEC for microorganisms:
- 9.5 mg/L
Additional information
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