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Diss Factsheets

Physical & Chemical properties

Vapour pressure

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Administrative data

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
September 27, 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance
Remarks:
(Knudsen cell)
Key result
Temp.:
20 °C
Vapour pressure:
0.07 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0.142 Pa

Vapour pressure of the test substance at 20 °C and 25 °C was calculated on the basis of equation log (P) = f (1/t) = a-b/(t+273.15) where P – vapour pressure in Pa, t – temperature in °C, obtained for four measurement points: 28.10 °C, 31.50 °C, 36.90 °C and 41.80 °C.

Conclusions:
The vapor pressure of the test substance was determined to be 0.07 Pa at 20 ºC and 0.142 Pa at 25 ºC.
Executive summary:

The study of vapour pressure using effusion method was performed in accordance with EU Method A.4 and OECD Guidance 104. GLP study. The vapor pressure of the test substance was determined to be 0.07 Pa at 20 ºC and 0.142 Pa at 25 ºC.

Description of key information

Key study: EU method A.4 and OECD Guidance 104. GLP study. The vapor pressure of the test substance was determined to be 0.07 Pa at 20 ºC and 0.142 Pa at 25 ºC.

Key value for chemical safety assessment

Vapour pressure:
0.142 Pa
at the temperature of:
25 °C

Additional information

Supporting: The estimated vapour pressure at 25 ºC was 0.0546 Pa (EPI-Suite, MPBPWIN v1.43)