Registration Dossier
Registration Dossier
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EC number: 201-132-3 | CAS number: 78-67-1
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- NOEC
- Effect concentration:
- 2.2 mg/L
Additional information
A Daphnia reproduction study was conducted according to OECD 202 but included reproduction for 21 days rather than 14 days, found that the 21 day 50% lethal concentration (LC50) in parental Daphnia magna was found to be >10 mg/L, whilst the 21 day 50% reproduction inhibition concentration (ErC50) was 7.5 mg/L (95% confidence interval 4.6 -10mg/L). The maximum no-observed-effect concentration (NOECr) was 2.2 mg/L and the lowest-observed-effect concentration (LOECr) was 4.6 mg/L.
Even if higher concentration could have been tested, the test has been carried out with concentrations allowing long-term exposures and is therefore considered as valid.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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