Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Ortho-toluene diamine, propoxylated was tested in the Guinea Pig Maximization Test (GPMT) on 15 female test animals (10 for the test item group, 5 control animals) for its skin sensitizing properties, according to the OECD Guideline 406. Concentrations of 5% (intradermal induction), 50% (topical induction and first challenge) and 25% (second challenge) of the test material in PEG 400 were used. Under the conditions of the test Ortho-toluene diamine, propoxylated was shown to exhibit no skin sensitization potential.


Migrated from Short description of key information:
Non-sensitiser using the guinea pig maximization test (GPMT), OECD 406

Justification for classification or non-classification

Results do not warrant classification.