Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sensitisation data (humans)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other: personal communication, mail of 26 Feb 2002
Title:
No information
Author:
Schnuch A
Year:
2002

Materials and methods

Type of sensitisation studied:
skin
Study type:
survey
Test guideline
Qualifier:
no guideline required
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N'-ethylenebis[N-acetylacetamide]
EC Number:
234-123-8
EC Name:
N,N'-ethylenebis[N-acetylacetamide]
Cas Number:
10543-57-4
Molecular formula:
C10H16N2O4
IUPAC Name:
N,N'-ethylenebis[N-acetylacetamide]

Method

Type of population:
general
Route of administration:
dermal

Results and discussion

Results of examinations:
According to IVDK (Information Network of Departments of Dermatology in Germany), where cases of skin sensitization are collected and evaluated centrally in Germany, cases of TAED-allergy have not been observed over the past 10 years, despite its widespread use.

Applicant's summary and conclusion