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Short-term toxicity to aquatic invertebrates

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Description of key information

The acute toxicity of tert-butyl peroxypivalate to invertebrates was assessed according to OECD guideline 202, EU method C.2 and OPPTS 850.1010. The 48 h EC50 value was determined as 6.99 mg/L, and the 48 h NOEC was determined to be 2.94 mg/L. The results are based on the measured geometric mean test item concentrations.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
6.99 mg/L

Additional information

The acute toxicity of tert-butyl peroxypivalate to invertebrates was assessed according to OECD guideline 202, EU method C.2 and OPPTS 850.1010. Young Daphnia magna were exposed in an immobilisation test to aqueous test media containing the test item for 48 hours at a range of concentration. Because the concentration of the test item was expected to decrease more than 20 % from the nominal during the exposure period, the test was performed under semi-static conditions. The frequency of the water renewal periods was 24 hours. Based upon the results from the preliminary experiments, nominal concentrations of 4.3; 9.4; 20.7; 45.5 and 100.0 mg/L were investigated in the main study. The measured concentrations deviated more than 20 % from the nominal during the experiments therefore the geometric mean of the measured concentrations were calculated in order to determine exposure concentrations. The corresponding calculated geometric mean concentrations were the followings: 2.94, 6.51, 14.44, 31.76 and 64.65 mg/L. In this 48-hour acute toxicity test with Daphnia magna the 48 h EC50 value was determined as 6.99 mg/L, and the 48 h NOEC was determined to be 2.94 mg/L. The results are based on the measured geometric mean test item concentrations.