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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

Arthur et al (1974) presents 96 hr TL50(or LC50) results of 103 and 125 mg/L NA3NTA for the fathead minnow, Pimephales promelas.  Tests were conducted according to APHA (1971) Standard Methods 13 ed.

Key value for chemical safety assessment

LC50 for freshwater fish:
103 mg/L

Additional information

Arthur et al (1974) presents 96 hr TL50(or LC50) results of 103 and 125 mg/L NA3NTA for the fathead minnow, Pimephales promelas. Tests were conducted according to APHA (1971) Standard Methods 13 ed.

This study was chosen as key study as it was the most sensitive reliable data for short-term toxicity of NTA to freshwater fish. Macek and Sturm (1973) provided 96 hr TL50 of 98 mg/L for exposure of Na3NTA to rainbow trout. This study was deemed unreliable. Weaver (1967) exposed blugill to Na3NTA in batch and flow-through tests, in soft and hard waters. This study was deemed reliable with restrictions as study was missing some testing information which did not affect the overall conclusion of the test.

Table 1. Summary of Short-term Toxicity to Fish

 Guideline  Species  Effect Concentration  Reference  Reliability
APHA (1971) Standard MEthods 13th ed.  Pimephales promelas  96hr LC50 = 103 and125 mg/L NTA  Arthur et al. (1974)  2- reliable with restrictions 
    summary of other data:LC50 >= 98 mg/L  Brouwer and Terpstra (1994)  4 - secondary literature 
 none followed  Salmo gairdneri (new name: Oncorhynchus mykiss) 96 hr TL50 = 98 mg/L  Macek and Sturm (1973)  3- not reliable
 Similar to OECD 203  Lepomis macrochirus  96 hr TLm:

soft water: continuous = 298 mg/L, batch = 270 mg/L Na3NTA

hard water: continuous = 510 mg/L, batch = 521 mg/L Na3NTA

Weaver (1967)   2 - reliable with restrictions