Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-568-5 | CAS number: 142-87-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48h EC50 (Daphnia magna, immobilization) > 100 mg/L (nominal concentration)
Key value for chemical safety assessment
Additional information
Two 24-hour tests with Daphnia magna are available for C10AS Na (CAS 142-87-0). The first non-GLP study followed a method described by Norme Francaise Homologue, 1983, NF T90-31 (Sanchez Leal 1991). The 24-hour EC50 value was 470 mg/L. Analytical check of the test concentrations was not provided. Since this study presents the most conservative 24-hour EC50 value, it was chosen as a key study. The other non-GLP study was performed following an AFNOR T.90301 (1974) method (Lundahl and Cabridenc 1978). The obtained results showed that the 24-hour EC50 value was 800 mg/L (nominal concentrations). Analytical measurements are not available. Since only limited information (24-hour tests) are available for aquatic invertebrates, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to other structurally related category members was conducted. Read-across data from C8AS Na (CAS 142-31-4) were used.
One GLP short-term toxicity test with Daphnia magna was performed with C8AS Na (CAS 142-31-4) according to OECD 202 guideline (Neven 1993). Daphnids were exposed under semi-static conditions to five test concentrations up to 100 mg/L (nominal concentrations in agreement with the measured ones). Based on mobility of daphnids, the 48-hour EC50 value was determined to be above 100 mg/L (nominal concentration). Moreover, three supporting 24-hour tests with Daphnia magna are available for C8AS Na (CAS 142-31-4). The non-GLP study of Richterich (2001) was performed according to OECD 202 guideline. Daphnids were exposed in a static test to fourteen different test concentrations up to the nominal concentration of 1000 mg/L. Analytical measurements are not available. The 24-hour EC50 value based on mobility was above 240 mg/L (nominal concentration). Lundahl (1978) reports a non-GLP test with Daphnia magna which was performed according to AFNOR T.90301 (1974) method. The result showed that the 24-hour EC50 value was 4350 mg/L. No analytical measurements were given. The last supporting study followed a method described by "Norme Francaise Homologue, 1983, NF T90-31" (Sanchez Leal 1991). The 24-hour test with Daphnia magna resulted in the EC50 value above 900 mg/L (nominal concentration, analytical measurements are not provided). Based on the presented results it can be concluded that the 48-hour EC50 value of C8AS Na (CAS 142-31-4) for aquatic invertebrates is above 100 mg/L.
Due to structural and property similarities with the tested category member, it can be concluded that the above results apply also to C10AS Na (CAS 142-87-0). Since the 24-hour EC50 values are in the same range as observed for C8AS Na (CAS 142-87-0), it can be expected that the 48-hour EC50 value for C10AS Na (CAS 142-87-0) will be above 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
