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Toxicity to microorganisms

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Description of key information

The effect of DOWANOL PnB Glycol Ether on activated sludge microorganisms was assessed by the Activated Sludge Respiration Inhibition Test
Method (OECD Guideline 209). The resulting 3-hr EC50 was >1000 mg/L.

Key value for chemical safety assessment

Additional information

One key study that assessed the effect of DOWANOL PnB Glycol Ether on microorganisms was available along with two supporting studies. In an activated sludge, respiration inhibition test, a 3hr EC50 > 1000 mg/L was reported. In a bacterial inhibition test the IC50 (16 hours) of Butyl PROPASOL Solvent was determined to be 1303 mg/L and the the EC50 (48 hours) of propylene glycol butyl ether in an Ames test (Salmonella typhimurium) was > 5000 µg/plate.