Registration Dossier
Registration Dossier
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EC number: 215-695-8 | CAS number: 1344-43-0
Repeated dose toxicity: dermal
Administrative data
- Endpoint:
- short-term repeated dose toxicity: dermal
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- A short-term toxicity study via the dermal route does not need to be conducted as the physiological properties of the substance do not suggest a significant rate of absorption through the skin and no systemic effects or other evidence of absorption were seen in the skin or eye irritation studies (IUCLID section 7.3) and furthermore the water solubility of the substance is very poor (IUCLID section 4.8), and therefore a limited amount of potential substance is available for systemic absorption via the dermal route. Therefore in accordance with Annex XI, section 1.1, this test is not considered necessary.
Data source
Materials and methods
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
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