Manganese oxide

Acute Toxicity: dermal

Administrative data

Endpoint:

acute toxicity: dermal

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Justification for type of information:

The physiochemical properties of MnO suggest it is unlikely to be absorbed through the skin. It has very poor water solubility and inorganic ions do not pass easily through the dermal barrier. In addition, MnO is not acutely toxic by the oral route and therefore it is highly unlikely that it would be toxic via the dermal route which in general absorbs chemicals to a much lesser degree than the gastrointestinal tract. Therefore in accordance with Annex VIII, section 8.5.3 column 2 adaptation, this test is not considered scientifically justified.