Registration Dossier
Registration Dossier
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EC number: 201-058-1 | CAS number: 77-78-1
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 14 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 3.8 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- sensitivity distribution
Hazard for air
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 2 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Additional information
No analytical determination was performed in any of the freshwater acute ecotoxicity studies. Therefore, in all cases the values based on the nominal concentration.
Another note must be made: DMS hydrolyses very fast (DT50 <1d) in water to monomethyl sulfate and methanol. Therefore, the toxicity/immobilisation and inhibition, respectively observed is predominantly based on the hydrolysis product monomethyl sulfate. This approach is conform to the guidance OECD series 23 (2000).
It could be excluded that the ecotoxicity effects observed are due to methanol (96 h LC50 fish: 19,000 mg/l; 24 h EC50 daphnids: >10,000 mg/l; EC50 algae: 36,000 mg/l, ECETOC, 1996) and therefore it can be concluded that the toxicity can mainly be attributed to DMS and methyl sulphate.
According to the EU RAR (2002); similarly to the PNECwater and the PNECmicroorganisms is based on the toxicity of DMS and its
hydrolysis products. However, due to the short exposure period (3 hours) in the activated sludge test the fraction of DMS will probably be higher than that in the aquatic tests (48-96 hours).
Conclusion on classification
The substance DMS has the following endpoint specific parameter which should be used to classify the substance:
96 hr LC50 (for fish): 14 mg/L
48 hr EC50 (for crustacea): 17 mg/L
72 hr ErC50 (for algae): 46.9 mg/L
Due to the results given above, the most sensitive species is the golden orfe with an LC50 (96h) of 14 mg/L.
Furthermore, in a screening test the substance was tested to be readily biodegradable. Therefore, and in accordance to regulation (EC) No.: 1272/2008 the substance does not have to classify as dangerous for the environment.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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