Registration Dossier

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Handbook data are considered to be from a trusted source.

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Patty, F (ed.).
Year:
1963
Bibliographic source:
Industrial Hygiene and Toxicology: Volume II: Toxicology. 2nd ed. New York: Interscience Publishers, 1963., p. 1889

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Diethyl oxalate
EC Number:
202-464-1
EC Name:
Diethyl oxalate
Cas Number:
95-92-1
Molecular formula:
C6H10O4
IUPAC Name:
diethyl oxalate
Details on test material:
- Name of test material: Diethyloxalate

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
400 - 1 600 mg/kg bw
Based on:
not specified
Gross pathology:
massive renal oxalate deposits were observed following treatment with 400 mg/kg bw or higher.

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria