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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

LL50 (96 h): > 1000 mg/l test mat. (nominal) and NOELR (96 h): >= 1000 mg/l test mat. (nominal) based on mortality of Brachydanio rerio (new name: Danio rerio).

Key value for chemical safety assessment

Additional information

A test medium prepared at a nominal loading rate 1000 mg/l of the test substance was not acutely toxic to Brachydanio rerio over 96 hours (96-h LL50: >1000 mg/L). A NOELR of ≥1000 mg/L was determined in the same test. In a second test, a 48-hour LL50 > 130 mg/l test mat. (dispersion) (nominal) was obtained with Oryzias latipes. In both tests, the LL50 and NOELR values significantly exceed the solubility of the substance (approximately 0.01 mg/l) and should therefore be taken to indicate that the test substance is unlikely to be toxic at its solubility limit.

The key study was selected because it was obtained in accordance with a guideline method for the endpoint and was assigned a higher reliability rating.

The registration substance itself appears to be non-toxic to freshwater fish at the solubility limit. Given the half-life of the hydrolysis reaction at pH7 and 25˚C, the chemical safety assessment focusses on the parent form.

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