Registration Dossier
Registration Dossier
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EC number: 402-070-1 | CAS number: 88122-99-0 UVINUL T 150
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
P criteria
The substance is not readily biodegradable according to both the ready biodegradability tests. Degradation of the the substance: 0% in 28 days (no degradation observed).
The substance is then considered to be persistent in the environment were exposure to occur based on the known lack of biodegradability.
B criteria
The measured bioconcentration factor (BCF) was found to be ca 80, wich means the material is not considered to have potential for bioaccumulation
T criteria
Eco-toxicity studies:
The toxicological examination on fish, daphnia and algae provided a LC50(96h) >1000 mg/L(Danio Rerio), an EC50(48h)> 500mg/L (Daphnia Magna) and an EC50 (72h)> 80 mg/L (Desmodesmus subspicatus).
Mammalian toxicity studies:
Also in this case the toxicological examination for genetic toxicity demonstrated a lack of mutagenic response.
The substance was not mutagenic or genotoxic when tested in vitro in a bacterial reverse mutation assay, a cell gene mutation test and an in vitro mammalian chromosome aberration assay.
A pre-natal developmental toxicity was conducted and no developmental toxicity was observed (NOAEL =1000 mg/kg bw/day).
Considering all the available toxicological information the substance can be assessed as not toxic.
The substance may pose a persistence (P) hazard but as the results produced no bioaccumulation (B) or toxicity (T) properties the substance cannot be considered as a PBT/vPvBT.
Since the criteria for B and T are not fulfilled, the substance is not PBT or vPvB
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