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EC number: 212-222-7
CAS number: 770-35-4
Non-GLP studies equivalent or similar to OECD guidelines 401 and 402 as well as GLP-studies according to OECD guidelines 402 and 403 are available for phenoxypropanol.
Oral: two non-GLP studies equivalent to OECD guideline 401
have been conducted with phenoxypropanol in rats. Both studies report
LD50 greater than 2000 mg/kg bw/day.
Dermal: in a GLP-study according to OECD guideline 402 the
dermal LD50 of phenoxypropanol in rats was greater than 2000 mg/kg bw.
This data is supported by a non-GLP study similar to OECD guideline 402
which reports a dermal LD50 greater than 2000 mg/kg bw in rabbits.
Inhalation: in a GLP-study according to OECD guideline 403
the LC50 of phenoxypropanol (liquid aerosol) was greater than 5.4 mg/L
(highest concentration tested). No mortality was observed in this study.
LD50 values for oral and dermal route are greater than 2000 mg/kg/bw and
no mortality has been observed after inhalation exposure to
phenoxypropanol up to the highest dose tested. According to the EU
criteria for classification and labeling, phenoxypropanol is not
classified for acute toxicity for any route of exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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