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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: A review of existing data. The investigations were performed with potassium bromate. A read across to sodium bromate is justified as both substances dissociated in water and Na+ and K+ ions are naturally occurring species.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
HSDB (Hazardous Substances Data Base) within TOXNET
Author:
HSDB
Year:
2013
Bibliographic source:
http://toxnet.nlm.nih.gov/
Reference Type:
publication
Title:
Toxicity of bromate to striped bass ichthyoplankton (Morone saxatilis) and juvenile spot (Leiostomus xanthurus).
Author:
Richardson LB; Burton DT; Rhoderick JC
Year:
1981
Bibliographic source:
J Toxicol Environ Health 8(4):687-95, 1981. Cited in HSDB (Hazardous Substances Data Base) 2013.

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Potassium bromate
EC Number:
231-829-8
EC Name:
Potassium bromate
Cas Number:
7758-01-2
IUPAC Name:
potassium bromate

Test organisms

Test organisms (species):
other: Striped bass (Morone saxatillis) eggs and larvae and juvenile spot (Leiostomus xanthurus)

Results and discussion

Effect concentrationsopen allclose all
Duration:
1 d
Dose descriptor:
LC50
Effect conc.:
698 mg/L
Nominal / measured:
nominal
Conc. based on:
other: bromate (BrO3-)
Remarks on result:
other: Data for juvenile spot.
Duration:
10 d
Dose descriptor:
LC50
Effect conc.:
279 mg/L
Nominal / measured:
nominal
Conc. based on:
other: bromate (BrO3-)
Remarks on result:
other: Data for juvenile spot.
Details on results:
Newly hatched striped bass prolarvae were most sensitive to bromate and had a 96-h LC50 of 30.8 mg/l (as BrO3-). Four-day-old striped bass larvae were less sensitive, with 2- to 10-d LC50s ranging from 605.0 to 92.6 mg/l BrO3-, respectively.
Juvenile spot, which is the age most comparable to standard acute ecotoxicity tests, were least sensitive, with 1- to 10-d LC50s ranging from 698.0 to 278.6 mg/l BrO3-, respectively.

Applicant's summary and conclusion

Conclusions:
Juvenile spot showed 1- to 10-d LC50s ranging from 698.0 to 278.6 mg/l BrO3-, respectively.
Executive summary:

Newly hatched striped bass prolarvae were most sensitive to bromate and had a 96-h LC50 of 30.8 mg/l (as BrO3-). Four-day-old striped bass larvae were less sensitive, with 2- to 10-d LC50s ranging from 605.0 to 92.6 mg/l BrO3-, respectively.

Juvenile spot (Leiostomus xanthurus), which is the age most comparable to standard acute ecotoxicity tests, were least sensitive, with 1- to 10-d LC50s ranging from 698.0 to 278.6 mg/l BrO3-, respectively.