Registration Dossier
Registration Dossier
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EC number: 204-699-5 | CAS number: 124-41-4
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Original report not available and documentation insufficient for assessment
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 979
- Report date:
- 1979
Materials and methods
- Principles of method if other than guideline:
- other: BASF test
- GLP compliance:
- no
Test material
- Reference substance name:
- Sodium methanolate
- EC Number:
- 204-699-5
- EC Name:
- Sodium methanolate
- Cas Number:
- 124-41-4
- Molecular formula:
- CH4O.Na
- IUPAC Name:
- sodium methanolate
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- other: Lutrol (G/V)
- Doses:
- 0.43 - 14.7% suspension in Lutrol (G/V)
- No. of animals per sex per dose:
- no information given
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 40 mg/kg bw
- Mortality:
- Deaths occurred within the first week of the experiment.
- Clinical signs:
- Uncharacteristic
- Body weight:
- body weight reduction in the beginning of the observation period
- Gross pathology:
- No macroscopic findings at necropsy
Applicant's summary and conclusion
- Conclusions:
- The acute intraperitoneal median lethal dose (LD50) in mice was determined to be 40 mg/kg bodyweight.
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