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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

Parent compound: Acutely harmful to fish.
Hydrolysis product: 2-Ethylhexanoic acid: Acutely harmful to fish.
Hydrolysis product: HCl: Acutely toxic for fish (pH-dependent).

Key value for chemical safety assessment

LC50 for freshwater fish:
66.3 mg/L

Additional information

The acute toxicity on fish was studied according to OECD 203 with Danio rerio under static conditions (BASF AG, 1998). The test item was 2 -ethylhexanoyl chloride, which is expected to hydrolyse rapidly. The test item concentrations were analytically verified, but are based on the hydrolysis product 2 -ethylhexanoic acid. The test item concentrations were initally in the range of 63.8% to 94.8% and after about 96 h between 43% and 86.2%. All fish died at the two highest test item concentration during the first day (nominal: 464 and 1000 mg/L; 1000 mg/L, pH-adjusted). Mortality occured also in the two lower test item concentrations (nominal: 100 and 215 mg/L).

The LC50 was calculated based on the mean measured concentrations: 96 -h LC50 = 66.3 mg/L.

The hydrolysis product 2 -ethylhexanoic acid was tested on Pimephales promelas in a static acute toxicity test according to test method 231 (US EPA). The substance is also not harmful to fish (96 -h LC50 70 mg/L; Waggy & Payne, 1974, as cited in OECD SIDS Documents, 2001).

The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 203 with Cyprinus carpio. The 96 -h LC50 was 4.92 mg/L (acid equivalent to pH 4.3; OECD 2002).