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Ecotoxicological information

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Cetrimonium chloride is readily biodegradable. However, based on the reliable guideline compliant studies, the 14 d NOEC values of the structurally similar test substance benzyl C12-16 alkyl dimethyl ammonium chloride in earthworm were 517 and 953 mg a.i./kg soil dw and LC0 values were >517 and 7,070 mg a.i./kg soil dw.

Further for the terrestial plants, the 16 d EC50 values of the structurally similar test substance benzyl C12-16 alkyl dimethyl ammonium chloride in soil, were 537, 634 and 1,960 mg a.i./kg soil dw for S. alba, T. pratense and T. aestivum, respectively.

Also, the activity of the micro-organisms transforming nitrogen in the soil was slightly inhibited by the structurally similar test substance test substance benzyl C12-16 alkyl dimethyl ammonium chloride at 50 mg a.i./kg. The EC50 calculated was 130 mg a.i./kg. Further, benzyl C12-16 alkyl dimethyl ammonium chloride have no long-term influence on nitrogen and carbon transformations in sandy loam and low humic content sand soils.

Therefore, it can reasonably be assumed that there is no significant long-term exposure of the substance to soil macro and micro-organisms

or birds and mammal. However, some toxicity was observed in the terrestial plants.