Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 214-604-9 | CAS number: 1163-19-5
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March - August 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed according to international guidelines and GLPs using the commercial product as test article.
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 002
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Bis(pentabromophenyl) ether
- EC Number:
- 214-604-9
- EC Name:
- Bis(pentabromophenyl) ether
- Cas Number:
- 1163-19-5
- Molecular formula:
- C12Br10O
- IUPAC Name:
- bis(pentabromophenyl) ether
- Details on test material:
- Test material was a composite of equal porportions of the commercial DecaBDE products of Albemarle Corp, Dead Sea Bromine Group, and Chemtura Corp.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 3 h
Test conditions
- Test temperature:
- 20 +-2 degrees C
Results and discussion
Effect concentrations
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 15 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
Any other information on results incl. tables
Treatment |
Concentration (mg/L) |
Respiration Rate (mg O2/L/hr) |
Percent Inhibition |
Control 1 |
NA |
41.6 |
NA |
Control 2 |
NA |
41.6 |
NA |
3,5-dichlorophenol |
3 |
39.0 |
6.3 |
3,5-dichlorophenol |
15 |
12.8 |
69.2 |
3,5-dichlorophenol |
50 |
4.9 |
88.2 |
DecaBDE |
15 |
40.0 |
3.9 |
DecaBDE |
15 |
43.4 |
-4.3 |
DecaBDE |
15 |
40.0 |
3.9 |
NA: Not applicable.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- Difference in respiration between the 2 controls < 15% differece established for the test.
- Conclusions:
- DecaBDE did not inhibit the respiration of activiated sewage sludge.
- Executive summary:
DecaBDE did not inhibit the respiration of activiated sewage sludge when tested at a concentration of 15 mg/L. The negative and positve controls performed as expected.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
