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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The results of one study conducted with 3 invertebrate species supported by a QSAR prediction.

Key value for chemical safety assessment

Additional information

A 96 hour acute toxicity test was conducted using three aquatic invertebrtate species ( Daphnia magna, Dugesia tigrina, and Helisoma trivolvis) and one fish species (Pimephales promelas). This study was performed in 1978, before promulgation of GLP regulations. Nevertheless, the design and performance of this test was consistent with the intent of GLPs. The procedure used in this study was similar to accepted methodologies of that time period. Details of the study are limited but considered reliable for a weight of evidence approach. The results indicate that no mortality was observed in any of the four species tested at a nominal concentration of 100 mg/L (96 hour LC50>100 mg/L). The results for the fish endpoint are supported by a later GLP study reported in section 6.1.1. Based upon a weight of evidence approach it is concluded that the 48 hour EC50 for aquatic invertebrates is > 100 mg/L.