Registration Dossier
Registration Dossier
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EC number: 614-074-2 | CAS number: 675106-31-7
Endpoint summary
Administrative data
Description of key information
Testing for irritation waived. Materials are inert and are unlikely to cause any irritation or corrosion other than transient mechanical itching. It is unethical to instil abrasive acicular particles into eyes. There are no reports of human eye irritation.
Key value for chemical safety assessment
Additional information
Justification for classification or non-classification
Various types of man-made mineral fibre have been shown to cause transient mechanical irritation in man. Referance: Stam Westerveld et al. Contact Dermatitis vol. 31 p. 1- 4 1994 , "Rubbing test responses of the skin to man made mineral fibres of different diameters" and this can be expected for this substance. However such mechanical and localised surface effect on the skin or eye differs from the chemical irritation modelled in available animal tests, and has not been considered by EU regulators as cause for classification as irritating (e.g. glass fibres, vitreous ceramic fibres). It is therefore predictable that the substance may cause minor and transient local irritation but does not warrant classification . Performance of new animal testing (especially in the eye) is therefore unjustifiable and unnecessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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