Registration Dossier
Registration Dossier
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EC number: 210-382-2 | CAS number: 614-45-9
Endpoint summary
Administrative data
Description of key information
Two 96h acute fish studies are available, however only one is considered valid as it was performed under semi-static conditions with analytical verification of the test solutions. The 96h-LC50 for this study was 1.6 mg/L based on measured concentrations.
One 48h acute study with Daphnia magna is available.The reported biological results were based on the mean measured test item concentrations. The 24- and 48- hour EC50s of the test item was calculated to be 11 mg/L with 95% Confidence limits of 7.7 and 16 mg/L.
Two studies on algae are available. One study on freshwater algae performed under GLP with measured concentrations of the parent compound is considered reliable.
The 72h-ErC50 for algae based on geomean measured concentrations is 0.8 mg/L, the ErC10 is 0.44 mg/L (geomean measured).
One chronic fish study is available. A study was performed to assess the effects of the test item on the early-life stages of the fathead minnow (Pimephales promelas) according to OECD guideline 210. No effects were found up to 0.072 mg/L. Post hatch survival turned out to be the critical endpoint in this study with an LC10 of 0.101 mg/L (geometric mean measured concentration).
The chronic toxicity to Daphnia magna was determined in a 21 -day semi-static test according to OECD guideline 211.
No significant effects were found up to 0.44 mg/L (TWA, equal to 1.0 mg/L nom.) on reproduction and parental length and weight. NOEC for these endpoints is equal to 0.44 mg/L (TWA).
The lowest EC10was found for reproduction and was 0.49 mg/L (TWA).
In order to predict effects of tert-butyl-peroxybenzoate in biological wastewater treatment plants, an activated sludge respiration inhibition test was performed according to the OECD 209 and the EEC Method C.11 Guidelines.
The 30min-EC50 of tert-butyl-peroxybenzoate for activated sludge is 43 mg/L. The 30min-EC10 is 6 mg/L.
Additional information
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