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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Because of the shorter than normal study duration and smaller than standard number of fish per concentration, the reliability of the absolute values cannot be assessed. However, the study is considered reliable for the trends in the data because the homologues were tested under identical conditions.

Data source

Reference
Reference Type:
publication
Title:
Reduction of aquatic toxicity of linear alkylbenzene sulfonate (LAS) by biodegradation.
Author:
Kimerle, R.A. and Swisher, R.D.
Year:
1977
Bibliographic source:
Water Research 11:31-37.

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: EPA-660/3-75-009 1975. Method for acute toxicity tests with fish, macroinvertebrates and amphibians.
Principles of method if other than guideline:
Acute toxicity tests were conducted on high molecular weight LAS, individual pure homologues, non-linear LAS components (dialkyl tetralin or indane sulfonates, DTIS), and model biodegradation intermediates (sulfophenylundecane, SOU) in order to determine whether biodegradation decreases toxicity. Toxicity tests were conducted in 5 L of 100 mg/L hardness water using 5 fathead minnows per concentration.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
1) High molecular weight LAS: Average chain length = 13.3; C11 1%, C12 8%, C13 52%, C14 39%
2) Individual LAS homologues of C10, C11, C12, C13, and C14
3) Nonlinear LAS components (DTIS)
4) Model biodegradation intermediates

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Pimephales promelas

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Post exposure observation period:
open-system

Test conditions

Hardness:
5 L of 100 mg/L hardness water
Reference substance (positive control):
not specified

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
1.7 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality

Any other information on results incl. tables

Fathead minnow LC50 (mg/L)

Average chain length

24 hour

48 hour

High molecular weight LAS

13.3

1.9

1.7

Individual homologues LAS

C10

10

48.0

43.0

C11

11

17.0

16.0

C12

12

4.7

4.7

C13

13

1.7

0.4

C14

14

0.6

0.4

Nonlinear LAS components (DTIS)

C10

10

87.0 ± 7.5

86.1 ± 15.0

C12

12

24.8 ± 5.8

21.5 ± 5.5

C14

14

8.1 ± 5.1

5.3 ± 3.9

Model biodegradation intermediates

C4 (SØ Butyrate)

4

~10,000

~10,000

C5 (SØ Valerate)

5

~10,000

~10,000

C11 (SØU)

11

85.9 ± 5.1*

76.6 ± 12.4*

*Subsequent repurification of this sample yielded a product with the same isomeric composition but with LC50 values over 1000 mg/L for fatheads.

Applicant's summary and conclusion