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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance with national standard methods (OECD) without GLP .
Qualifier:
according to
Guideline:
OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)
Deviations:
no
GLP compliance:
no
Type of method:
other: slow-stirring method
Partition coefficient type:
octanol-water
Analytical method:
other: two-phase titration
Type:
log Pow
Partition coefficient:
1.5
Temp.:
23 °C
pH:
6 - <= 7
   determination 1  determination 2  determination 3
temperature 23 °C
stirring velocity 100 r/min
volume of flask 250 ml
amount of test substance 371 mg 110 mg 213 mg
volume of water 200 ml 100 ml 50 ml
volume of octanol 20 ml 20 ml 100 ml
 duration of stirring  24 h
 molecular weight of test substance 471
 concentration of titrant (Hyamine) 0.004 mol/l
 factor of titrant 0.979
 used volume of octanol layer of totration 1 ml 1 ml  5 ml
 consumption of titration of octanol layer 6.86 ml 2.26 ml 4.45 ml 
 amount of test substance in octanol layer 253.06 mg 83.37 mg 164.15 mg
 used volume of aqueous layer for titration 10 ml 20 ml 10 ml
consumption of titration of aqueous layer 1.53 ml 1.51 ml 0.37 ml
amount of test substance in aqueous layer 56.44 mg 13.93 mg 3.41 mg
concentration in aqueous layer 0.28 g/l 0.14 g/l 0.07 g/l
total amount of test substance recovered  309.50 mg 97.29 mg 167.57 mg
recovery rate 94 % 99 % 88 %
measured concentration in octanol layer 26.86 mmol/l 8.85 mmol/l 3.49 mmol/l
measured concentration in aqueous layer 0.60 mmol/l 0.30 mmol/l 0.14 mmol/l
log Pow 1.7 1.5 1.4
log Pow (mean value) 1.5
Conclusions:
The measured log Pow of Benzenesulfonic acid, C10-13-alkyl derivs., compds. with triethanolamine was determined to be 1.5 at 23 °C and a pH of 6 - 7.
Executive summary:

The log Pow of the test substance Benzenesulfonic acid, C10-13-alkyl derivs., compds. with triethanolamine was determined according to OECD Guideline 123 (Partition Coefficient (1 -Octanol / Water), Slow-Stirring Method).

The log Pow was determined to be 1.5 at 23 °C and a pH of 6 - 7.

Description of key information

log Pow = 1.5 at 23 °C; pH 6 - 7

Key value for chemical safety assessment

Log Kow (Log Pow):
1.5
at the temperature of:
23 °C

Additional information