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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Study only available as summary in the ECB iuclid dataset for 3-chloropropane-1,2-diol (European Commission-European Chemicals Bureau-19 Feb 2000-http://ecb.jrc.eu/esis/index.php?GENRE=CASNO&ENTREE=9624-2).

Data source

Reference
Title:
The comparative effects of|1,2-dibromo-3-chloropropane (DBCP) and his metabolites,|3-chloro-1,2-propaneoxide (Epichlorohydrin),|3-chloro-1,2-propanediol (alpha-Chlorohydrin), and oxalic|acid, on the urogenital system of male rats
Author:
Kluwe W.M.
Year:
1983
Bibliographic source:
Toxicol. Appl. Pharmacol., 70, 67-86.

Materials and methods

Principles of method if other than guideline:
other
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloropropane-1,2-diol
EC Number:
202-492-4
EC Name:
3-chloropropane-1,2-diol
Cas Number:
96-24-2
Molecular formula:
C3H7ClO2
IUPAC Name:
3-chloropropane-1,2-diol

Test animals

Species:
rat

Administration / exposure

Route of administration:
subcutaneous

Results and discussion

Applicant's summary and conclusion