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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Study only available as summary in the ECB iuclid dataset for 3-chloropropane-1,2-diol (European Commission-European Chemicals Bureau-19 Feb 2000-http://ecb.jrc.eu/esis/index.php?GENRE=CASNO&ENTREE=9624-2).

Data source

Reference
Title:
Structure-activity studies with chlorohydrins as orally active male antifertility agents
Author:
Paul R. et al
Year:
1974
Bibliographic source:
Contraception, 9(5), 451-57.

Materials and methods

Principles of method if other than guideline:
Method: other
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloropropane-1,2-diol
EC Number:
202-492-4
EC Name:
3-chloropropane-1,2-diol
Cas Number:
96-24-2
Molecular formula:
C3H7ClO2
IUPAC Name:
3-chloropropane-1,2-diol

Test animals

Species:
rat

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
55 mg/kg bw

Applicant's summary and conclusion

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