Registration Dossier
Registration Dossier
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EC number: 202-492-4 | CAS number: 96-24-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Study only available as summary in the ECB iuclid dataset for 3-chloropropane-1,2-diol (European Commission-European Chemicals Bureau-19 Feb 2000-http://ecb.jrc.eu/esis/index.php?GENRE=CASNO&ENTREE=9624-2).
Data source
Reference
- Title:
- Structure-activity studies with chlorohydrins as orally active male antifertility agents
- Author:
- Paul R. et al
- Year:
- 1 974
- Bibliographic source:
- Contraception, 9(5), 451-57.
Materials and methods
- Principles of method if other than guideline:
- Method: other
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-chloropropane-1,2-diol
- EC Number:
- 202-492-4
- EC Name:
- 3-chloropropane-1,2-diol
- Cas Number:
- 96-24-2
- Molecular formula:
- C3H7ClO2
- IUPAC Name:
- 3-chloropropane-1,2-diol
Constituent 1
Test animals
- Species:
- rat
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- 55 mg/kg bw
Applicant's summary and conclusion
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