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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Specific investigations: other studies

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Administrative data

Endpoint:
biochemical or cellular interactions
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Study only available as summary in the ECB iuclid dataset for 3-chloropropane-1,2-diol (European Commission-European Chemicals Bureau-19 Feb 2000-http://ecb.jrc.eu/esis/index.php?GENRE=CASNO&ENTREE=9624-2).

Data source

Reference
Title:
Mode of action of alpha-chlorohydrin as a male antifertility agent : inhibition of the metabolism of ram spermatozoa by alpha-chlorohydrin and location of block in glycolysis
Author:
Brown-Woodman P.D. et al
Year:
1978
Bibliographic source:
Biochem. J., 170, 23-37.

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloropropane-1,2-diol
EC Number:
202-492-4
EC Name:
3-chloropropane-1,2-diol
Cas Number:
96-24-2
Molecular formula:
C3H7ClO2
IUPAC Name:
3-chloropropane-1,2-diol

Results and discussion

Applicant's summary and conclusion