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Toxicological information

Specific investigations: other studies

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Administrative data

Endpoint:
biochemical or cellular interactions
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Study only available as summary in the ECB iuclid dataset for 3-chloropropane-1,2-diol (European Commission-European Chemicals Bureau-19 Feb 2000-http://ecb.jrc.eu/esis/index.php?GENRE=CASNO&ENTREE=9624-2).

Data source

Reference
Title:
Mode of action of alpha-chlorohydrin as a male antifertility agent : inhibition of the metabolism of ram spermatozoa by alpha-chlorohydrin and location of block in glycolysis
Author:
Brown-Woodman P.D. et al
Year:
1978
Bibliographic source:
Biochem. J., 170, 23-37.

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloropropane-1,2-diol
EC Number:
202-492-4
EC Name:
3-chloropropane-1,2-diol
Cas Number:
96-24-2
Molecular formula:
C3H7ClO2
IUPAC Name:
3-chloropropane-1,2-diol

Results and discussion

Applicant's summary and conclusion